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NGHIÊN CỨU TÁC DỤNG GIẢM ĐAU CỦA CAO LỎNG CÂY THUỐC THƯỢNG TRÊN ĐỘNG VẬT THỰC NGHIỆM
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Abstract
The research aims to evaluate the analgesic effect of aqueous extract of Phaeanthus vietnamensis Ban on white mice. Materials and Methods: Evaluation of the central analgesic effect by using the pain-induced Hotplate model and the Writhing tests model with acetic acid. Results: The group was used aqueous extract of Phaeanthus vietnamensis Ban had a statistically significant greater time of pain occurrence (p < 0.05) compared to the control group and similar to the reference group (Diclofenac); the number of writhing pain, during 25 minutes after acetic acid injection, in both groups with dose 1 and dose 2 were statistically significantly lower (p < 0.01), equivalent to the reference group (Diclofenac). Conclusions: Aqueous extract from leaves of Phaeanthus vietnamensis Ban at a oral doses of 2,4 g/kg/day and 4,8 g/kg/day has good analgesic effect according to peripheral analgesic mechanism
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Keywords
Pain relief, Phaeanthus vietnamensis Ban.
References
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