RESEARCH ON COMMON SYMPTOMS AND CLINICAL PATTERNS IN CHRONIC KIDNEY DISEASE PATIENTS ACCORDING TO TRADITIONAL MEDICINE

Trần Thị Tuyết Nhung, Phạm Xuân Phong

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Objective: To describe common symptoms and clinical patterns in Chronic kidney disease (CKD) patients according to traditional medicine. Research method: A cross-sectional descriptive research was conducted on 1,020 patients diagnosed with CKD based on modern medical criteria. Results: (1) Common symptoms of CKD in traditional medicine include reduced sexual activity, lower back pain, knee weakness, joint pain, tinnitus, dizziness, fatigue, poor appetite, nocturia, yellow and scanty urine, constipation, pale swollen tongue, yellow sticky or white slippery tongue coating, and sublingual varices. (2) Common clinical patterns according to traditional found in CKD patients include five root syndrome patterns: Energy-Yin dual deficiency (31.57%), Spleen-Kidney energy deficiency (28.24%), Spleen-Kidney Yang deficiency (18.43%), Yin-Yang dual  deficiency (17.35%), Liver-Kidney Yin deficiency (2.84%) And four branch syndrome patterns: Phlegm-Dampness (68.73%), Dampness-Heat (21.18%), Blood stasis (12.16%), Water-Dampness (7.75%). Patients with Spleen-Kidney Yang deficiency and Yin-Yang dual deficiency had an average glomerular filtration rate (GFR) of 28.1±17.14 ml/min/1.73m² and 26.9±16.25 ml/min/1.73m², respectively, which was lower than that of patients with Spleen-Kidney Energy deficiency, Energy-Yin dual deficiency, and Liver-Kidney Yin deficiency (35.61±18.25 ml/min/1.73m², 36.19±18.42 ml/min/1.73m², and 42.93±14.24 ml/min/1.73m², respectively; p < 0.05). Patients with Water-Dampness pattern had an average GFR of 28.7±16.16 ml/min/1.73m², which was lower than those with Blood stasis (35.11±17.16 ml/min/1.73m²) and Dampness Heat patterns (34±17.21 ml/min/1.73m²); p < 0.05. Conclusions: Common clinical symptoms of CKD according to traditional medicine are mainly related to the Spleen-Kidney organs. The root syndrome patterns include Energy-Yin dual deficiency, Spleen-Kidney Energy deficiency, Spleen-Kidney Yang deficiency, Yin-Yang dual  deficiency, and Liver-Kidney Yin deficiency. The branch syndrome patterns often seen are Phlegm-Dampness, Dampness-Heat, Blood stasis, and Water-Dampness. Patients with Spleen-Kidney Yang deficiency and Yin-Yang dual  deficiency have lower GFR compared to other root syndrome patterns, and those with Water-Dampness have lower GFR than those with Blood stasis and Dampness-Heat patterns

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